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COVID-19 Update – Critical Care and Pandemic Response
In the midst of rising COVID-19 case rates globally, Derek C. Angus, MD, MPH and Rochelle P. Walensky, MD, MPH return to JAMA's Q&A series to update viewers on developments in the pandemic and the critical care management of COVID-19 patients. Dr. Angus is Chief Health Care Innovation Officer at @upmc, Professor and Chair of Critical Care Medicine, and a senior JAMA editor. Dr. Walensky is Chief of Infectious Diseases at @MassGeneralHospital and a Professor at @Harvard Medical School. Recorded November 19, 2020.

Topics discussed in this interview:
0:00 Introduction
0:54 US COVID-19 data update
1:26 Intubation and current standard of care
4:37 Corticosteroids
7:30 Therapies (steroids, remdesivir, tocilizumab)
10:21 Questions about remdesivir
12:30 Tocilizumab trials and press releases
17:07 Making decisions based on press releases vs clinical trials
19:18 Potential of additional therapies (cyclosporine, interferon beta, etc.)
23:44 Pre-Thanksgiving surge in cases
26:46 What is sustainable in prevention and hospital capacity
31:30 mRNA vaccines (Pfizer and Moderna) and distribution
35:11 Safety data and mRNA vaccines

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